Protzilla
Breaking the data wall to make programmable enzymes.
AI-guided enzyme optimization for teams that measure hundreds of variants, not millions.
Validated by leading researchers.
Product.
Tell us your enzyme. We tell you what to test.
Your protein engineering campaigns fail because complex AI models need too much data. We make Bio+AI work for you. Submit your sequence and measurements. Protzilla proposes the next batch of variants to synthesize in your directd evolution campaign.
The best out of billions.
Protzilla scores every possible mutation and selects the 25-200 candidates most likely to improve your enzyme.
Your lab. Your assay. Your data.
Run your standard assay on the proposed variants. Activity, stability, selectivity. If you can measure it, we can improve it.
Every round gets smarter.
The model learns from your new measurements and expands its search into deeper mutational space. Fewer experiments, faster results.
Results.
Proven in the lab.
By operating on data collected by you, our models minimize costs and maximize insights gained from your lab work.
Matching high-throughput results with a fraction of the screening.
Higher chance of finding the best variants vs. previous methods.
3/5 enzymes improved by 5-15× over 3 rounds with < 100 variants tested.
7× production rate of biofuel by optimizing a cyclopropanase.
3 rounds. <100 variants.
Team.
From the AI cluster to the lab bench.
Finn Lueth
Bioinformatics @ TUM & LMU.
